No. 12 Florida at Miami
When: 11 a.m. Saturday TV: ESPN
Where: Sun Life Stadium, Miami Line: Florida by 3
What’s up: It doesn’t matter where the game is played or how each team is playing; this one’s always a bitter battle between athletic, talented teams. Look for the Gators to wear down the ’Canes with a strong second-half run game.
My pick: Florida 31-21
No. 2 Oregon at Virginia
When: 2:30 p.m. Saturday TV: ESPN2
Where: Scott Stadium, Charlottesville Line: Oregon by 21½
What’s up: The Ducks take their quick-strike, hyper-frenetic offense all the way across the country … and the jet lag is about all that will slow them down (but not much). Sorry, Cavaliers, but you’re outgunned and overmatched.
My pick: Oregon 51-21
No. 6 South Carolina at No. 11 Georgia
When: 3:30 p.m. Saturday TV: ESPN
Where: Sanford Stadium, Athens Line: Georgia by 3
What’s up: The Bulldogs don’t want to fall to 0-2 and see their BCS title hopes finished before Week 3. The Gamecocks want to kick Georgia while it’s down. The winner will get an early leg up in the SEC East race.
My pick: Georgia 27-24
West Virginia at No. 16 Oklahoma
When: 6 p.m. Saturday TV: Fox
Where: Gaylord Family Memorial Stadium, Norman Line: Oklahoma by 20½
What’s up: The Sooners always reload, and this year is no exception. The Mountaineers lost key pieces on offense, but the questionable defense of 2012 is a year older and wiser. Still, Oklahoma is too much at home.
My pick: Oklahoma 34-14
No. 14 Notre Dame at No. 17 Michigan
When: 7 p.m. Saturday TV: ESPN
Where: Michigan Stadium, Ann Arbor Line: Michigan by 3½
What’s up: It’s the last time these two rivals will meet at the Big House, at least for the forseeable future. I have little doubt it will be a classic, as usual, but I think Devin Gardner will outplay Tommy Rees and conduct “Hail to the Victors” during the postgame celebration.
My pick: Michigan 38-34