Jerian Grant scored 21 points, including a big three-point play in overtime, to lift No. 21 Notre Dame to an 82-78 win over DePaul on Wednesday night in South Bend, Ind.
It was the second overtime win for the Irish (20-5, 8-4 Big East) over the Blue Demons (10-14, 1-10) in 11 days.
DePaul used an 11-1 run to take a 58-57 lead, but the Irish rallied 4 days after beating Louisville in five overtimes.
Jack Cooley had 16 points and 10 rebounds for the Irish.
Cleveland Melvin led DePaul with 23 points
No. 1 Indiana 76, Nebraska 47: Cody Zeller cored 16 points, and Christian Watford finished with 13 points and 11 rebounds to help the Hoosiers pull away in Indianapolis.
The Hoosiers (22-3, 10-2 Big Ten) have won seven of eight. Dylan Talley led Nebraska (12-13, 3-9) with 16 points, 10 in the first half.
No. 2 Duke 73, North Carolina 68: Mason Plumlee had 18 points and 11 rebounds for the Blue Devils in Durham, N.C.
Quinn Cook added 18 points for the Blue Devils (22-2, 9-2 Atlantic Coast Conference).
P.J. Hairston scored 20 points and Reggie Bullock had 15 points with four 3s for North Carolina (16-8, 6-5), which led for the first 26 minutes.
Connecticut 66, No. 6 Syracuse 58: Freshman Omar Calhoun scored 15 points, including three 3-pointers in a deciding second-half run, and Connecticut won in Hartford, Conn., in the last scheduled game between the national powers.
Syracuse (20-4, 8-3 Big East) is bound for the Atlantic Coast Conference, while Connecticut (17-6, 7-4) will stay in the realigned Big East.
Charlotte 71, No. 11 Butler 67: Pierria Henry scored 17 points to help Charlotte to an upset in Indianapolis.
The 49ers (18-6, 6-4) went on a 7-1 run to take a 59-49 lead late.
Rotnei Clarke scored 18, and Roosevelt Jones had 17 points and nine rebounds to lead the Bulldogs (20-5, 7-3 Atlantic 10).
Ball State 56, Northern Illinois 52: Jauwan Scaife scored 23 points, including four free throws in the final 35 seconds, to lift Ball State past Northern Illinois in DeKalb.
Scaife was just 6-for-18 from the floor but 9-for-10 from the line for the Cardinals (10-13, 4-7 Mid-American).
Antone Christian had 14 points for NIU (5-18, 3-8).
Illinois State 79, Bradley 59: After leading just 32-31 at the half, the Redbirds blew things open in a Missouri Valley tilt in Normal.
Jackie Carmichael led ISU (16-10, 7-7) with 27 points, while Tyler Brown added 22. Walt Lemon Jr. led the Braves (14-12, 6-8) with 15 points.
Southern Illinois 65, Evansville 56: In Carbondale, Jeff Early scored 14 points, grabbed 10 rebounds and the Salukis won for only the third time since the calendar turned to 2013.
Southern Illinois (10-15, 3-11 Missouri Valley) shot 46.7 percent from the floor and won 26-9 in bench points. Colt Ryan scored 21 points on 7-of-15 shooting including five 3-pointers and grabbed four rebounds to lead Evansville (14-12, 7-7).