CAIRO (AP) – Egyptians delivered an angry backlash against President Mohammed Morsi and his Muslim Brotherhood on Friday, marking the second anniversary of the start of the country’s revolution with tens of thousands filling major squares and streets around the country to call for a new regime change.

Two years to the day that protesters first rose up against now-toppled autocrat Hosni Mubarak, Egypt is entrenched in the new phase of its upheaval – the struggle between ruling Islamists and their opponents, played out on the backdrop of a worsening economy.

Rallies turned to clashes near Tahrir Square and outside the presidential palace in Cairo and in multiple cities around the country, with police firing tear gas and protesters throwing stones. At least four people, including a 14-year-old boy, were killed in the day’s worst clashes, in the city of Suez, where protesters set ablaze a building that once housed the city’s local government.