DePaul’s first appearance of the season at Allstate Arena was a dud Thursday.
Visiting Gardner-Webb claimed a 71-59 victory in a Cancun Challenge opening-round game, outperforming the Blue Demons.
Guard Max Landis scored a game-high 20 points for the Running’ Bulldogs (2-2) in the teams’ first meeting.
Cleveland Melvin paced the Blue Demons (1-1) with 18 points and eight rebounds, and Brandon Young added 10 points.
Northwestern 81, Mississippi Valley State 68: Mississippi Valley junior transfer Davon Usher scored a game-high 35 points to single-handedly keep the Delta Devils in the game in Evanston, but Northwestern got key late baskets from sophomore guard Dave Sobolewski.
Sobolewski scored his first field goal of the season on a layup to break a 58-58 tie midway through the second half moments after Usher had hit a 3.
Sobolewski scored all 13 of his points, including two 3-point baskets, down the stretch to give Northwestern (2-0) the victory.
No. 1 Indiana 99, Sam Houston State 45: Christian Watford scored 23 points in a Progressive Legends Classic game in Bloomington, Ind.
Will Sheehey scored 18 points, Victor Oladipo had 14 and Jordan Hulls 10 for the Hoosiers (3-0).
Iowa 66, Howard 36: The Hawkeyes rode a lopsided first half to victory in Iowa City, Iowa.
Devyn Marble led all scorers with 22, and Iowa led 36-16 at the break.
Illinois State 86, Drexel 84: Jackie Carmichael scored a game-high 21 points and the Redbirds edged the Dragons 11-9 in the extra session in Philadelphia.